Monoclonal antibodies for the treatment of cancer: A brief overview
DOI:
https://doi.org/10.33064/iycuaa2024924653Keywords:
monoclonal antibodies, hybridoma, cancer, antigens, antibodies, adverse effectsAbstract
Immunotherapy is a powerful tool in the treatment of chronic-degenerative diseases such as cancer, is targeted at the immune system to trigger strong memory immune response and are key in treatment against tumor cells through long-term anti-tumor immune response and cell death by binding specific to target antigens and the activation of various mechanisms, with low toxicity and minimal described adverse events. The FDA has approved 31 monoclonal antibodies, but side effects still occur. Therefore, our objective was to present a bibliographic review in MEDLINE and academic Google on the advances, uses, mechanisms of action and unwanted effects of monoclonal antibodies in the treatment of cancer.
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Copyright (c) 2024 Dharana Gutiérrez-Chávez, María Fernanda Gómez-Valencia , Itzel Viridiana Reyes-Pérez , María Evarista Arellano-García, Olivia Torres-Bugarín
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