Genetics of overweight and obesity in Mexican children and adolescents
DOI:
https://doi.org/10.33064/iycuaa2022863630Keywords:
Overweight, obesity, genes, genetic polymorphisms, Mexican children, Mexican adolescentsAbstract
Overweight and obesity affect more than 340 million children and adolescents worldwide, constituting a serious public health issue. Common obesity is a multifactorial disease mainly caused by poor diet and low physical activity, but also some genes play a role in its development. Thus, our objective was to perform a literature review to identify genes associated with overweight and obesity in Mexican children and adolescents. Thirty-six percent of the genes analyzed, 8/22, showed significant association for overweight/obesity, these genes are: FGF21, FTO, GNPDA2, HP, MC4R, PAI1, PCSK1, and PON1. Therefore, we can affirm that genetic background plays an important key in the etiology of overweight and obesity in Mexican children and adolescents. However, we must remember that hypercaloric diet and sedentary lifestyle are still the main causes of overweight and obesity common around the world.
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Copyright (c) 2022 Angélica López-García, Verónica Judith Picos-Cárdenas, Evelia Leal-Ugarte, Saúl Armando Beltrán-Ontiveros, Juan Pablo Meza-Espinoza
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