In vitro anti-inflammatory activity of the ethanolic and hexanic extracts of Cuscuta jalapensis Schltdl.'s stems
DOI:
https://doi.org/10.33064/iycuaa2018751766Keywords:
anti-inflammatory, membrane stability, erythrocyte, lysosome, extractAbstract
In this work, the in vitro anti-inflammatory activity of ethanolic and hexanic extracts of Cuscuta jalapensis Schltdl. was evaluated by using the erythrocyte membrane stability model against two agents inducing hemolysis, the hypotonic saline solution and heat. A phytochemical sieve was used to determine the families of secondary metabolites present in both extracts being alkaloids and flavonoid principally. A concentration response curve of the antiinflammatory activity was drawn, starting from 50, 100, 200 and 400 μg/ml, of both extracts, using 100μg/ml indomethacin as the pharmacological control. The results indicated that all tested concentrations of the different extracts decreased hemolysis and therefore produced a membrane stabilizing effect. For evaluation with hypotonic saline the ethanolic extract had an effect equal to indimetacin 100 μg/ ml, the concentrations of the hexane extract showed a lower anti-inflammatory activity in this test
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