Atypical case of IgA nephropathy: A practical review of the diagnostic protocol in Mexico

Abstract

IgA nephropathy is one of the most common immunecomplex mediated primary glomerulonephritis in the world, affecting approximately 1.5% of the global population. In this analysis, we present the case of a 24-year-old male patient of Mexican nationality with a history of hypertension for 1 year and 3 months, and development of lower extremity edema for 6 months. During the study protocol, elevated creatinine and urea levels were found along with proteinu-ria in the nephrotic range without microscopic hematuria; a renal biopsy was performed, showing mesangial proliferation and podocyte hyperplasia, along with IgA and IgM mesangial deposits, confirming the diagnosis of IgA nephropathy.