Skeletal muscle biopsy: an important approach to exercise physiology research
DOI:
https://doi.org/10.33064/iycuaa2021844161Keywords:
Biopsies, exercise, ethics, physiology, skeletal muscleAbstract
Beginning in the 60s, muscle biopsies, along with biochemical studies have improved the understanding of exercise physiology. The advancement in the technique of biopsies and the development of molecular biology have allowed greater understanding about the molecular regulation of metabolism in muscle fibers and their adaptation to exercise. However, the usefulness of biopsies has been questioned by arguing that the risk of the procedure could be greater than the benefit. The aim of the present work was to review the literature on the safety and efficacy of skeletal muscle biopsy for the study of exercise. This review shows that, performed correctly and by an expert, skeletal muscle biopsy is a safe, low-risk procedure and is an effective tool for the investigation of exercise physiology.
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