Antigenic proteins of Acanthamoeba castellanii involved in adhesion
DOI:
https://doi.org/10.33064/iycuaa2013583991Keywords:
Acanthamoeba castellanii, antigenic proteins, adhesionAbstract
Acanthamoeba castellanii is an opportunistic pathogen agent causing infections such as keratitis, encephalitis and skin infections. Actually, the acantamoebiosis is a health problem, with unselective and toxic drugs. The adhesion ability of A.castellanii by tissues of the host cell is essential to the development of infection. This study analyzes the antigenic proteins and their role in adherence
of the parasite to the host cells. The results show eight antigenic proteins of Mr ≤ 180, 174, 124, 113, 84, 49, 43 and 40 kDa, localized in the trophozoite surface. Furthermore the parasite-host interaction assays using polyclonal antibodies, indicating a decrease in adhesion (90%) of the trophozoite to the host cell.
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Copyright (c) 2013 José Alberto Juárez Rodríguez, Gloria Barbosa Sabanero, José de Jesús Serrano Luna, Lérida Liss Flores Villavicencio, Mineko Shibayama Salas, Myrna Sabanero López
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
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